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Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50017658
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603750(CHEMBL5178459)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50585017(CERALASERTIB | Ceralasertib | Atr kinase inhibitor...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603751(CHEMBL5179068)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603769(CHEMBL5198456)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603749(CHEMBL5188748)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603748(CHEMBL5192680)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603768(CHEMBL5192689)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603752(CHEMBL5192206)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603766(CHEMBL5174833)
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603758(CHEMBL5172908)
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603755(CHEMBL5190917)
Affinity DataIC50: 115nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603739(CHEMBL5199317)
Affinity DataIC50: 183nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603742(CHEMBL5180045)
Affinity DataIC50: 194nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603759(CHEMBL5186625)
Affinity DataIC50: 215nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603738(CHEMBL5186126)
Affinity DataIC50: 275nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603745(CHEMBL5203170)
Affinity DataIC50: 289nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603753(CHEMBL5184308)
Affinity DataIC50: 435nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603741(CHEMBL5176656)
Affinity DataIC50: 578nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603770(CHEMBL5208355)
Affinity DataIC50: 609nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603746(CHEMBL5180248)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603767(CHEMBL5203964)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603754(CHEMBL5172751)
Affinity DataIC50: 901nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603762(CHEMBL5176352)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603750(CHEMBL5178459)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant B-raf (416 to end residue) using myelin-Bas as substrate incubated for 40 mins in presence of ATP by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603744(CHEMBL5190044)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603747(CHEMBL5196853)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603743(CHEMBL5169778)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603737(CHEMBL5188769)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603760(CHEMBL5198149)
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603761(CHEMBL5200343)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603757(CHEMBL5172957)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603756(CHEMBL5187392)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603763(CHEMBL5184782)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603765(CHEMBL5177557)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603764(CHEMBL5204030)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603771(CHEMBL5194198)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603773(CHEMBL5201457)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603740(CHEMBL5197038)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603772(CHEMBL5182460)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603775(CHEMBL5193604)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603774(CHEMBL5194672)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603777(CHEMBL5182302)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603776(CHEMBL5174332)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603778(CHEMBL5206229)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed