Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50018105
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557717BDBM50557717(CHEMBL4743666)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404039BDBM50404039(CHEMBL5289941)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404036BDBM50404036(CHEMBL5076091)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Mouse)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404035BDBM50404035(CHEMBL5287177)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant His-tagged mouse KIF18A expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule-stimulated ATPase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404000BDBM50404000(CHEMBL5279604)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404034BDBM50404034(CHEMBL5077043)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404037BDBM50404037(CHEMBL5287302)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403677BDBM50403677(CHEMBL5288088)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404035BDBM50404035(CHEMBL5287177)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404033BDBM50404033(CHEMBL5083562)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404030BDBM50404030(CHEMBL5278809)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403999BDBM50403999(CHEMBL5276902)
Affinity DataIC50: 165nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404031BDBM50404031(CHEMBL5270982)
Affinity DataIC50: 166nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403678BDBM50403678(CHEMBL5276935)
Affinity DataIC50: 253nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403675BDBM50403675(CHEMBL5081638)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403676BDBM50403676(CHEMBL5284647)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403557BDBM50403557(CHEMBL5084830)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403553BDBM50403553(CHEMBL5266739)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403674BDBM50403674(CHEMBL5083490)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403556BDBM50403556(CHEMBL5287687)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404038BDBM50404038(CHEMBL1990168)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403673BDBM50403673(CHEMBL5267992)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403613BDBM50403613(CHEMBL5273486)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403555BDBM50403555(CHEMBL5282084)
Affinity DataIC50: 5.31E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403554BDBM50403554(CHEMBL5282512)
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403646BDBM50403646(CHEMBL5285875)
Affinity DataIC50: 8.88E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403645BDBM50403645(CHEMBL5274941)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404037BDBM50404037(CHEMBL5287302)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of KIF18A ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404037BDBM50404037(CHEMBL5287302)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to KIF18A (unknown origin) by NMR based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404035BDBM50404035(CHEMBL5287177)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403554BDBM50403554(CHEMBL5282512)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Eg5 assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403553BDBM50403553(CHEMBL5266739)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Eg5 assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403554BDBM50403554(CHEMBL5282512)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403553BDBM50403553(CHEMBL5266739)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Amgen Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404035BDBM50404035(CHEMBL5287177)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Eg5 assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed