Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50016722
TargetGolgi-associated PDZ and coiled-coil motif-containing protein(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50596828(CHEMBL4783570)
Affinity DataKd:  490nMAssay Description:Binding affinity to CAL PDZ domain (unknown origin) assessed as dissociation constant in presence of tris(carboxylethyl)phosphine by fluorescence ani...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594267(CHEMBL5189477)
Affinity DataIC50: 362nMAssay Description:Inhibition of PARP16 (unknown origin) using 6xHis-tagged IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human PARP3 expressed in baculovirus expression system using anchored-histone proteins as substrate incubated for 1 hr by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594267(CHEMBL5189477)
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of recombinant human PARP3 expressed in baculovirus expression system using anchored-histone proteins as substrate incubated for 1 hr by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of PARP16 (unknown origin) using 6xHis-tagged IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetGolgi-associated PDZ and coiled-coil motif-containing protein(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50596827(CHEMBL5177006)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of CAL PDZ domain (unknown origin) assessed as inhibition constant by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetGolgi-associated PDZ and coiled-coil motif-containing protein(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50596826(CHEMBL5202803)
Affinity DataKi:  2.26E+4nMAssay Description:Inhibition of CAL PDZ domain (unknown origin) assessed as inhibition constant by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetGolgi-associated PDZ and coiled-coil motif-containing protein(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50596825(CHEMBL5196216)
Affinity DataKi:  3.90E+5nMAssay Description:Inhibition of wild type CAL PDZ domain (unknown origin) expressed in Escherichia coli Rosette 2 (DE3) assessed as inhibition constant incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed