Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50015058
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582304BDBM50582304(CHEMBL5072213)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582301BDBM50582301(CHEMBL5091256)
Affinity DataIC50: 160nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019315BDBM50019315(CHEMBL3289420)
Affinity DataIC50: 180nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582293BDBM50582293(CHEMBL5075517)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582305BDBM50582305(CHEMBL5091818)
Affinity DataIC50: 210nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582302BDBM50582302(CHEMBL5072152)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019324BDBM50019324(CHEMBL3289398)
Affinity DataIC50: 330nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019316BDBM50019316(CHEMBL3289421)
Affinity DataIC50: 370nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582313BDBM50582313(CHEMBL5093823)
Affinity DataIC50: 420nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582302BDBM50582302(CHEMBL5072152)
Affinity DataIC50: 470nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582300BDBM50582300(CHEMBL5074659)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582314BDBM50582314(CHEMBL5076121)
Affinity DataIC50: 540nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582333BDBM50582333(CHEMBL5088110)
Affinity DataIC50: 590nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582300BDBM50582300(CHEMBL5074659)
Affinity DataIC50: 600nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582320BDBM50582320(CHEMBL5089364)
Affinity DataIC50: 600nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582299BDBM50582299(CHEMBL5091051)
Affinity DataIC50: 640nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582330BDBM50582330(CHEMBL5094886)
Affinity DataIC50: 650nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582319BDBM50582319(CHEMBL5082214)
Affinity DataIC50: 740nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582321BDBM50582321(CHEMBL5090345)
Affinity DataIC50: 780nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582334BDBM50582334(CHEMBL5093028)
Affinity DataIC50: 780nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582332BDBM50582332(CHEMBL5080399)
Affinity DataIC50: 920nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582328BDBM50582328(CHEMBL5080842)
Affinity DataIC50: 990nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582331BDBM50582331(CHEMBL5071620)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582316BDBM50582316(CHEMBL5077311)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582312BDBM50582312(CHEMBL5084657)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582315BDBM50582315(CHEMBL5094505)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582309BDBM50582309(CHEMBL5091868)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582296BDBM50582296(CHEMBL5089676)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582296BDBM50582296(CHEMBL5089676)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582305BDBM50582305(CHEMBL5091818)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582299BDBM50582299(CHEMBL5091051)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582300BDBM50582300(CHEMBL5074659)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582329BDBM50582329(CHEMBL5091418)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582293BDBM50582293(CHEMBL5075517)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582306BDBM50582306(CHEMBL5083095)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582294BDBM50582294(CHEMBL5092554)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582297BDBM50582297(CHEMBL5082744)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582301BDBM50582301(CHEMBL5091256)
Affinity DataIC50: 4.53E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582310BDBM50582310(CHEMBL5088652)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582295BDBM50582295(CHEMBL5081532)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582326BDBM50582326(CHEMBL5080196)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582308BDBM50582308(CHEMBL5089657)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582311BDBM50582311(CHEMBL5081206)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582292BDBM50582292(CHEMBL5087053)
Affinity DataIC50: 7.39E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582296BDBM50582296(CHEMBL5089676)
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582304BDBM50582304(CHEMBL5072213)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582307BDBM50582307(CHEMBL5087593)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582317BDBM50582317(CHEMBL5092630)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582318BDBM50582318(CHEMBL5087954)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582292BDBM50582292(CHEMBL5087053)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
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