Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50016301
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant p300 HAT domain using histone H4 peptide and acetyl-coA as substrates preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50255529(Ac-Lys(CoA)-NH2 | CHEMBL505121)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant p300 (unknown origin) using mixed histones and acetyl-coA as substrates incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of p300 HAT domain (unknown origin) using histone H4-15 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50151658(CHEMBL3775671)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human p300 HAT catalytic domain using histone H3 peptide and acetyl-coA as substrates preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCREB-binding protein(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human CBP-HAT domain using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594047(CHEMBL5189948)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567480(CHEMBL4862454)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142083(CHEMBL3758664)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of biotinylated histone H4 peptide binding to His-tagged human p300 HAT domain (1195 to 1673 residues) assessed as reduction in alpha sign...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567474(CHEMBL4867031)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594041(CHEMBL5179924)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567477(CHEMBL4852716)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567484(CHEMBL4861102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594046(CHEMBL5175438)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594045(CHEMBL5188583)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594029(CHEMBL5208421)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594031(CHEMBL5175603)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594030(CHEMBL5194564)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594033(CHEMBL5181216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594032(CHEMBL5179838)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594035(CHEMBL5190567)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594034(CHEMBL5191477)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594037(CHEMBL5192617)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594036(CHEMBL5204412)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594038(CHEMBL5183894)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594040(CHEMBL5191177)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594042(CHEMBL5186215)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142084(CHEMBL3758284)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594043(CHEMBL5185050)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142245(CHEMBL3758933)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142086(CHEMBL3758396)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594044(CHEMBL5196404)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50594039(CHEMBL5207744)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567460(CHEMBL4868257)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142083(CHEMBL3758664)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of biotinylated histone H4 peptide binding to His-tagged human p300 HAT domain (1195 to 1673 residues) assessed as reduction in alpha sign...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142247(CHEMBL3759745)
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50140251(CHEMBL3759614)
Affinity DataIC50: 6.26E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Myst3 using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PCAF using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed