Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50016077
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592034(CHEMBL5201794)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592035(CHEMBL5206775)
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592033(CHEMBL5196498)
Affinity DataIC50: 33nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592036(CHEMBL5175891)
Affinity DataIC50: 43nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 77nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592037(CHEMBL5200495)
Affinity DataIC50: 121nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592038(CHEMBL5204954)
Affinity DataIC50: 134nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592035(CHEMBL5206775)
Affinity DataIC50: 364nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592037(CHEMBL5200495)
Affinity DataIC50: 614nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592034(CHEMBL5201794)
Affinity DataIC50: 648nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592036(CHEMBL5175891)
Affinity DataIC50: 839nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592039(CHEMBL5179538)
Affinity DataIC50: 965nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592038(CHEMBL5204954)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592039(CHEMBL5179538)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592033(CHEMBL5196498)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed