Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50016105
LigandPNGBDBM50592373(CHEMBL5180031)
Affinity DataEC50:  22nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592371(CHEMBL5203914)
Affinity DataEC50:  41nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592366(CHEMBL5190632)
Affinity DataEC50:  107nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592363(CHEMBL5173841)
Affinity DataEC50:  113nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592364(CHEMBL5204350)
Affinity DataEC50:  136nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592372(CHEMBL5202497)
Affinity DataEC50:  142nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592370(CHEMBL5180378)
Affinity DataEC50:  159nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592368(CHEMBL5177312)
Affinity DataEC50:  184nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592362(CHEMBL5181801)
Affinity DataEC50:  188nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592365(CHEMBL5187015)
Affinity DataEC50:  190nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592367(CHEMBL5172188)
Affinity DataEC50:  210nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  241nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592369(CHEMBL5178099)
Affinity DataEC50:  321nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  1.78E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  1.78E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  1.94E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50504991(CHEMBL4438246)
Affinity DataEC50:  2.01E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50504988(CHEMBL4586969)
Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592361(CHEMBL5173199)
Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50504991(CHEMBL4438246)
Affinity DataEC50:  2.52E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  2.61E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50504988(CHEMBL4586969)
Affinity DataEC50:  2.72E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed