Compile Data Set for Download or QSAR
Report error Found 188 Enz. Inhib. hit(s) with all data for entry = 50017294
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600864(CHEMBL5179849)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600917(CHEMBL5195088)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600889(CHEMBL5202312)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600891(CHEMBL5208283)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600865(CHEMBL5205616)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600888(CHEMBL5179644)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600881(CHEMBL5185917)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600885(CHEMBL5187007)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600937(CHEMBL5169846)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600936(CHEMBL5194188)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600938(CHEMBL5192641)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600880(CHEMBL5181631)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600877(CHEMBL5203424)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600871(CHEMBL5201759)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600907(CHEMBL5197238)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600923(CHEMBL5186180)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600862(CHEMBL5172228)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600895(CHEMBL5196411)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600848(CHEMBL5190772)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600890(CHEMBL5196750)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600879(CHEMBL5188254)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600852(CHEMBL5199615)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600927(CHEMBL5193367)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600878(CHEMBL5169343)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600896(CHEMBL5183964)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600930(CHEMBL5191001)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600934(CHEMBL5191057)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600897(CHEMBL5184916)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600900(CHEMBL5198565)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600882(CHEMBL5180856)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600899(CHEMBL5208333)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600872(CHEMBL5205549)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600925(CHEMBL5205005)
Affinity DataEC50:  0.320nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600863(CHEMBL5196512)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600935(CHEMBL5194475)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600849(CHEMBL5176430)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600884(CHEMBL5193298)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600866(CHEMBL5207112)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600853(CHEMBL5172955)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600870(CHEMBL5181859)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600939(CHEMBL5170841)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600915(CHEMBL5206742)
Affinity DataEC50:  0.520nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600926(CHEMBL5182713)
Affinity DataEC50:  0.540nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600916(CHEMBL5185479)
Affinity DataEC50:  0.570nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600898(CHEMBL5205713)
Affinity DataEC50:  0.590nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600865(CHEMBL5205616)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600892(CHEMBL5174119)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600930(CHEMBL5191001)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50600917(CHEMBL5195088)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
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