Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50016356
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50553869(CHEMBL4764965)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594444(CHEMBL5174214)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594445(CHEMBL5195838)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50258966(CHEMBL4071151)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594446(CHEMBL5169325)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50553869(CHEMBL4764965)
Affinity DataEC50: <100nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594445(CHEMBL5195838)
Affinity DataEC50:  265nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594444(CHEMBL5174214)
Affinity DataEC50:  380nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594449(CHEMBL5200766)
Affinity DataEC50: >500nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594447(CHEMBL5178181)
Affinity DataEC50: >900nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594448(CHEMBL5203494)
Affinity DataEC50:  1.09E+3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594450(CHEMBL5184750)
Affinity DataEC50: <3.00E+3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594451(CHEMBL5181040)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594446(CHEMBL5169325)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50258966(CHEMBL4071151)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)