Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50017000
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM18012(trans,trans-4-arylpiperidine-based compound, 1)
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598963(CHEMBL5174310)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212579(US9278944, 270 | US10155731, Example 270)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212579(US9278944, 270 | US10155731, Example 270)
Affinity DataIC50: 0.450nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598963(CHEMBL5174310)
Affinity DataIC50: 0.700nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant glycosylated human renin expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598961(CHEMBL5200104)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598954(CHEMBL5187830)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212577(US9278944, 268 | US10155731, Example 268)
Affinity DataIC50: 1.40nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598965(CHEMBL5188936)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598954(CHEMBL5187830)
Affinity DataIC50: 1.80nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598961(CHEMBL5200104)
Affinity DataIC50: 2.60nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598960(CHEMBL5176170)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212577(US9278944, 268 | US10155731, Example 268)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212580(US9278944, 271 | US10155731, Example 271)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598965(CHEMBL5188936)
Affinity DataIC50: 6.5nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598962(CHEMBL5190224)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM18012(trans,trans-4-arylpiperidine-based compound, 1)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM149462(US8975252, 39)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598960(CHEMBL5176170)
Affinity DataIC50: 19nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598962(CHEMBL5190224)
Affinity DataIC50: 33nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598964(CHEMBL5199696)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM149462(US8975252, 39)
Affinity DataIC50: 84nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598959(CHEMBL5184827)
Affinity DataIC50: 159nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598956(CHEMBL5192644)
Affinity DataIC50: 453nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598959(CHEMBL5184827)
Affinity DataIC50: 661nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598955(CHEMBL5177599)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598958(CHEMBL5176704)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598957(CHEMBL5194608)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed