Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50017015
TargetUDP-glucuronosyltransferase 1A1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM13934(CGP 73547 | CHEMBL1163 | methyl N-[(1S)-1-{[(2S,3S...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM13934(CGP 73547 | CHEMBL1163 | methyl N-[(1S)-1-{[(2S,3S...)
Affinity DataIC50: 600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50599144(CHEMBL5179012)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50599144(CHEMBL5179012)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50599144(CHEMBL5179012)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed