Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50018538
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50: 90nMAssay Description:Inhibition of his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataKd:  650nMAssay Description:Binding affinity to his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) assessed as dissociation constant by surface plasmon reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50: 900nMAssay Description:Inhibition of his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609347(CHEMBL5268922)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) assessed as dissociation constant by surface plasmon reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609349(CHEMBL5283603)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609349(CHEMBL5283603)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609349(CHEMBL5283603)
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) assessed as dissociation constant by surface plasmon reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataKd:  7.20E+3nMAssay Description:Binding affinity to his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609349(CHEMBL5283603)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) in human NCI-H1993 cells by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609347(CHEMBL5268922)
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) in human NCI-H1993 cells by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed