Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50017329
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601257BDBM50601257(CHEMBL5178276)
Affinity DataIC50: 48nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601254BDBM50601254(CHEMBL5190048)
Affinity DataIC50: 61nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601255BDBM50601255(CHEMBL5172911)
Affinity DataIC50: 69nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601258BDBM50601258(CHEMBL5198248)
Affinity DataIC50: 93nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 260nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601256BDBM50601256(CHEMBL5193934)
Affinity DataIC50: 440nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601253BDBM50601253(CHEMBL5172081)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601252BDBM50601252(CHEMBL5171569)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed