Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50016580
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50595789(CHEMBL5200746)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50595789(CHEMBL5200746)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed