Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50018565
TargetCytochrome P450 4F11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106737(N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamid...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant CYP4F11 using Luciferin ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4Z1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609596(CHEMBL5272822)
Affinity DataIC50: 42nMAssay Description:Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4Z1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609594(CHEMBL5267609)
Affinity DataIC50: 90nMAssay Description:Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4Z1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609597(CHEMBL5274921)
Affinity DataIC50: 109nMAssay Description:Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4F12(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106737(N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamid...)
Affinity DataIC50: 155nMAssay Description:Inhibition of human recombinant CYP4F12 using Luciferin ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4F11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609596(CHEMBL5272822)
Affinity DataIC50: 291nMAssay Description:Inhibition of human recombinant CYP4F11 using Luciferin ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4Z1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609595(CHEMBL5279945)
Affinity DataIC50: 519nMAssay Description:Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4Z1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106737(N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamid...)
Affinity DataIC50: 601nMAssay Description:Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 4F12(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609596(CHEMBL5272822)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant CYP4F12 using Luciferin ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106737(N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamid...)
Affinity DataIC50: 6.32E+3nMAssay Description:Inhibition of human recombinant CYP2C9 using Luciferin CEE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106737(N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using Luciferin-IPA as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609596(CHEMBL5272822)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using Luciferin-IPA as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106737(N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 using Luciferin-ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609596(CHEMBL5272822)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 using Luciferin CEE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609596(CHEMBL5272822)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 using Luciferin-ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed