Compile Data Set for Download or QSAR
Report error Found 105 Enz. Inhib. hit(s) with all data for entry = 50019265
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human SRPK3 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataIC50: 3nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SRPK3 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617299(CHEMBL5439515)
Affinity DataIC50: 7nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617308(CHEMBL5397100)
Affinity DataIC50: 15nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617311(CHEMBL5416930)
Affinity DataIC50: 15nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617310(CHEMBL5409896)
Affinity DataIC50: 16nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM221074(US9695160, 12 | SPHINX31 | US9796707, Compound 12)
Affinity DataIC50: 17nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617296(CHEMBL5422948)
Affinity DataIC50: 18nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataEC50:  20nMAssay Description:Inhibition of N-terminal nLuc-fused SRPK3 (unknown origin) transfected in lysed HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617300(CHEMBL5398076)
Affinity DataIC50: 22nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617307(CHEMBL5409387)
Affinity DataIC50: 24nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617301(CHEMBL5416263)
Affinity DataIC50: 24nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataIC50: 27nMAssay Description:Inhibition of human SRPK3 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617305(CHEMBL5403164)
Affinity DataIC50: 31nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617297(CHEMBL5407046)
Affinity DataIC50: 32nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617298(CHEMBL5399262)
Affinity DataIC50: 32nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617312(CHEMBL5437009)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617294(CHEMBL5433267)
Affinity DataIC50: 36nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataEC50:  40nMAssay Description:Inhibition of N-terminal nLuc-fused SRPK3 (unknown origin) transfected in intact HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataEC50:  44nMAssay Description:Inhibition of C-terminal nLuc-fused SRPK1 (unknown origin) transfected in lysed HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617292(CHEMBL5434661)
Affinity DataIC50: 58nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM221074(US9695160, 12 | SPHINX31 | US9796707, Compound 12)
Affinity DataEC50:  60nMAssay Description:Inhibition of C-terminal nLuc-fused SRPK1 (unknown origin) transfected in intact HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617306(CHEMBL5435975)
Affinity DataIC50: 65nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataIC50: 80nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617304(CHEMBL5421441)
Affinity DataIC50: 81nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataIC50: 83nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataEC50:  98nMAssay Description:Inhibition of C-terminal nLuc-fused SRPK1 (unknown origin) transfected in intact HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617313(CHEMBL5405335)
Affinity DataIC50: 107nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataKd:  145nMAssay Description:Binding affinity to SRPK1 (unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617306(CHEMBL5435975)
Affinity DataIC50: 147nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617308(CHEMBL5397100)
Affinity DataIC50: 147nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617302(CHEMBL5085558)
Affinity DataEC50:  149nMAssay Description:Inhibition of N-terminal nLuc-fused SRPK2 (unknown origin) transfected in lysed HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617295(CHEMBL5415454)
Affinity DataIC50: 152nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 159nMAssay Description:Inhibition of human CLK4 using myelin basic protein as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617293(CHEMBL5416898)
Affinity DataIC50: 164nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM221074(US9695160, 12 | SPHINX31 | US9796707, Compound 12)
Affinity DataIC50: 166nMAssay Description:Inhibition of human SRPK3 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617313(CHEMBL5405335)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 225nMAssay Description:Inhibition of human DYRK1A using RRRFRPASPLRGPPK as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM221074(US9695160, 12 | SPHINX31 | US9796707, Compound 12)
Affinity DataIC50: 256nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617299(CHEMBL5439515)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM221074(US9695160, 12 | SPHINX31 | US9796707, Compound 12)
Affinity DataIC50: 266nMAssay Description:Inhibition of human CLK4 using myelin basic protein as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 293nMAssay Description:Inhibition of human DYRK1B using RRRFRPASPLRGPPK as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617311(CHEMBL5416930)
Affinity DataIC50: 300nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617291(CHEMBL5417678)
Affinity DataIC50: 324nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617312(CHEMBL5437009)
Affinity DataIC50: 340nMAssay Description:Inhibition of human SRPK2 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50617303(CHEMBL5409358)
Affinity DataIC50: 357nMAssay Description:Inhibition of human SRPK1 using GRSRSRSRSR as substrate in presence of [gamma-33p]-ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSRSF protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50235034(CHEMBL4064277)
Affinity DataEC50:  398nMAssay Description:Inhibition of N-terminal nLuc-fused SRPK3 (unknown origin) transfected in intact HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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