Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50019528
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620134BDBM50620134(CHEMBL5416045)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620142BDBM50620142(CHEMBL5425916)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620137BDBM50620137(CHEMBL5424678)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620152BDBM50620152(CHEMBL5413871)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620139BDBM50620139(CHEMBL5400242)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620153BDBM50620153(CHEMBL5409508)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620150BDBM50620150(CHEMBL5400174)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620140BDBM50620140(CHEMBL5425722)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620138BDBM50620138(CHEMBL5435280)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620146BDBM50620146(CHEMBL5427297)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620135BDBM50620135(CHEMBL5424938)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620151BDBM50620151(CHEMBL5435720)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620136BDBM50620136(CHEMBL5438114)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620143BDBM50620143(CHEMBL5420177)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620145BDBM50620145(CHEMBL5428030)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620144BDBM50620144(CHEMBL5401231)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620141BDBM50620141(CHEMBL5432309)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620148BDBM50620148(CHEMBL5395324)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620149BDBM50620149(CHEMBL5406574)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620147BDBM50620147(CHEMBL5405848)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of PCSK9 transcriptional activity in human HepG2 cells stably expressing luciferase reporter plasmid containing PCSK9 promoter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed