Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50019277
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617517(CHEMBL5398230)
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617518(CHEMBL5429169)
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617514(CHEMBL5394292)
Affinity DataIC50: 130nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617524(CHEMBL5429742)
Affinity DataIC50: 340nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 490nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617521(CHEMBL5437686)
Affinity DataIC50: 600nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617525(CHEMBL5400728)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617522(CHEMBL5410024)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617520(CHEMBL5432569)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617531(CHEMBL5431470)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617526(CHEMBL5394722)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617523(CHEMBL5438340)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617530(CHEMBL5409403)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617528(CHEMBL5408567)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617515(CHEMBL5406223)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617527(CHEMBL5423082)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617529(CHEMBL5418006)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617519(CHEMBL5417655)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50617516(CHEMBL5407878)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using [2,8-3H]dGTP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed