Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50018832
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613007(CHEMBL5290432)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613008(CHEMBL5288483)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613008(CHEMBL5288483)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613007(CHEMBL5290432)
Affinity DataEC50:  75nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613009(CHEMBL5280172)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613011(CHEMBL5291340)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613010(CHEMBL5276128)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613008(CHEMBL5288483)
Affinity DataEC50:  230nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613009(CHEMBL5280172)
Affinity DataEC50:  240nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613011(CHEMBL5291340)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613010(CHEMBL5276128)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613007(CHEMBL5290432)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613007(CHEMBL5290432)
Affinity DataEC50:  610nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613007(CHEMBL5290432)
Affinity DataEC50:  740nMAssay Description:Agonist activity at FLAG-tagged mouse kappa opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613011(CHEMBL5291340)
Affinity DataEC50:  930nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613009(CHEMBL5280172)
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613010(CHEMBL5276128)
Affinity DataEC50:  1.22E+3nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  2.25E+3nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataEC50:  5.24E+3nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed