Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50019668
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621634(CHEMBL5439740)
Affinity DataIC50: 150nMAssay Description:Inhibition of human factor XIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621636(CHEMBL5415361)
Affinity DataIC50: 180nMAssay Description:Inhibition of thrombin in human plasma measured after 10 mins by chromogenic substrate hydrolysis assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621631(CHEMBL5438187)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant FXIa assessed as S-2366 hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621633(CHEMBL559721)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human factor XIaMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM85682(CAS_5311315 | NSC_5311315 | NF279)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human Factor XIa assessed as substrate hydrolysis measured after 10 mins by chromogenic substrate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621635(CHEMBL1851651)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human factor XIaMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621632(CHEMBL5414212)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human Factor XIa assessed as substrate hydrolysis measured after 10 mins by chromogenic substrate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor X(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50621633(CHEMBL559721)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human factor XaMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed