Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50020153
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  670nMAssay Description:Agonist activity at Gal4-fused FXR LBD (unknown origin) transfected in HEK293T cells co-transfected with Peak12-Gal4UAS-luci assessed as receptor tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50626855(CHEMBL5401788)
Affinity DataEC50:  980nMAssay Description:Agonist activity at Gal4-fused FXR LBD (unknown origin) transfected in HEK293T cells co-transfected with Peak12-Gal4UAS-luci assessed as receptor tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50626855(CHEMBL5401788)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at FXR (unknown origin) assessed as SRC2 recruitment by LanthaScreen TR-FRET FXR coactivator assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50626856(CHEMBL5420654)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at Gal4-fused FXR LBD (unknown origin) transfected in HEK293T cells co-transfected with Peak12-Gal4UAS-luci assessed as receptor tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50626857(CHEMBL5396265)
Affinity DataEC50:  7.10E+3nMAssay Description:Agonist activity at Gal4-fused FXR LBD (unknown origin) transfected in HEK293T cells co-transfected with Peak12-Gal4UAS-luci assessed as receptor tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed