Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50020701
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632902(CHEMBL5435821)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632908(CHEMBL5409410)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632903(CHEMBL5405004)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632901(CHEMBL5416117)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632907(CHEMBL5402477)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632904(CHEMBL5411825)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632915(CHEMBL5440319)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632897(CHEMBL5425043)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 19(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to GSK3B (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632910(CHEMBL5423457)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632897(CHEMBL5425043)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to GSK3B (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to GSK3A (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632914(CHEMBL5429467)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632899(CHEMBL5417604)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632917(CHEMBL5432423)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632897(CHEMBL5425043)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to GSK3A (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632906(CHEMBL5427899)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50: 14nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  15nMAssay Description:Binding affinity to CLK1 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632909(CHEMBL5416134)
Affinity DataIC50: 17nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase LATS2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  18nMAssay Description:Binding affinity to LATS2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataKd:  20nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632900(CHEMBL5412471)
Affinity DataIC50: 36nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  36nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCasein kinase I isoform gamma-3(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  37nMAssay Description:Binding affinity to CSNK1G3 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase LATS2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  38nMAssay Description:Binding affinity to LATS2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataKd:  39nMAssay Description:Binding affinity to GSK3B (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  43nMAssay Description:Binding affinity to CLK1 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  56nMAssay Description:Binding affinity to GSK3B (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataKd:  64nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataKd:  68nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  68nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataKd:  71nMAssay Description:Binding affinity to CLK1 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataKd:  74nMAssay Description:Binding affinity to GSK3A (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632916(CHEMBL5397969)
Affinity DataIC50: 80nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632897(CHEMBL5425043)
Affinity DataKd:  82nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632912(CHEMBL5436530)
Affinity DataIC50: 83nMAssay Description:Inhibition of His tagged human recombinant CDK8/Cyclin C expressed in baculovirus expression system incubated for 15 mins by FRET-based LanthaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632897(CHEMBL5425043)
Affinity DataKd:  86nMAssay Description:Binding affinity to CLK1 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataKd:  89nMAssay Description:Binding affinity to CLK1 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  120nMAssay Description:Binding affinity to GSK3A (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCasein kinase I isoform gamma-3(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  150nMAssay Description:Binding affinity to CSNK1G3 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataKd:  210nMAssay Description:Binding affinity to GSK3B (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataKd:  240nMAssay Description:Binding affinity to GSK3A (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase LATS2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataKd:  250nMAssay Description:Binding affinity to LATS2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
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