Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50019535
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620271BDBM50620271(CHEMBL5410073)
Affinity DataIC50: 16nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620282BDBM50620282(CHEMBL5396505)
Affinity DataIC50: 35nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620283BDBM50620283(CHEMBL5412510)
Affinity DataIC50: 47nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620268BDBM50620268(CHEMBL5433570)
Affinity DataIC50: 62nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 64nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620268BDBM50620268(CHEMBL5433570)
Affinity DataIC50: 65nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620271BDBM50620271(CHEMBL5410073)
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620276BDBM50620276(CHEMBL5429693)
Affinity DataIC50: 110nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 120nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620272BDBM50620272(CHEMBL5415246)
Affinity DataIC50: 130nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620286BDBM50620286(CHEMBL5420601)
Affinity DataIC50: 150nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620276BDBM50620276(CHEMBL5429693)
Affinity DataIC50: 160nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620275BDBM50620275(CHEMBL5414870)
Affinity DataIC50: 180nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620269BDBM50620269(CHEMBL5437481)
Affinity DataIC50: 250nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620279BDBM50620279(CHEMBL5431839)
Affinity DataIC50: 420nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620277BDBM50620277(CHEMBL5409169)
Affinity DataIC50: 560nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620275BDBM50620275(CHEMBL5414870)
Affinity DataIC50: 630nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620279BDBM50620279(CHEMBL5431839)
Affinity DataIC50: 630nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620283BDBM50620283(CHEMBL5412510)
Affinity DataIC50: 720nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620270BDBM50620270(CHEMBL5395810)
Affinity DataIC50: 730nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620286BDBM50620286(CHEMBL5420601)
Affinity DataIC50: 790nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620273BDBM50620273(CHEMBL5420876)
Affinity DataIC50: 890nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620281BDBM50620281(CHEMBL5399948)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620282BDBM50620282(CHEMBL5396505)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620285BDBM50620285(CHEMBL5399017)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620280BDBM50620280(CHEMBL5419475)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620285BDBM50620285(CHEMBL5399017)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620278BDBM50620278(CHEMBL5409137)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620284BDBM50620284(CHEMBL5409678)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620277BDBM50620277(CHEMBL5409169)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620269BDBM50620269(CHEMBL5437481)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620278BDBM50620278(CHEMBL5409137)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620274BDBM50620274(CHEMBL5407734)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620280BDBM50620280(CHEMBL5419475)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620274BDBM50620274(CHEMBL5407734)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620284BDBM50620284(CHEMBL5409678)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620281BDBM50620281(CHEMBL5399948)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620273BDBM50620273(CHEMBL5420876)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620270BDBM50620270(CHEMBL5395810)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620272BDBM50620272(CHEMBL5415246)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of full-length recombinant human HDAC1 (1 to 482 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Tfa)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed