Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50018962
TargetMetabotropic glutamate receptor 7(Mouse)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614232(CHEMBL5266235)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614234(CHEMBL5285249)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614232(CHEMBL5266235)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614233(CHEMBL5280256)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614231(CHEMBL5288955)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614235(CHEMBL5286456)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM58360(MLS001173561 | N,N'-dibenzhydrylethane-1,2-diamine...)
Affinity DataEC50:  64nMAssay Description:Agonist activity at human mGluR7b expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614239(CHEMBL5272418)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human mGluR7b expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614236(CHEMBL5291195)
Affinity DataEC50:  113nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614238(CHEMBL5281755)
Affinity DataEC50:  156nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50614237(CHEMBL5289481)
Affinity DataEC50:  1.35E+3nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at mGluR7 (unknown origin) assessed as inhibition of L-AP4 stimulated decrease in forskolin induced cAMP response by CRE-Luc assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)