Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50019291
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 0.5nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 5.80nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 36nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 80nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataKd: 220nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Norwegian University of Science and Technology (Ntnu
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair






















3D Structure (crystal)










