Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50019291
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617728BDBM50617728(CHEMBL5415149 | US20250353857, Compound TIA05-014)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617725BDBM50617725(CHEMBL5404686 | US20250353857, Compound TIA04-051)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617728BDBM50617728(CHEMBL5415149 | US20250353857, Compound TIA05-014)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617720BDBM50617720(CHEMBL5407395 | US20250353857, Compound TIA03-188)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617721BDBM50617721(CHEMBL5431736 | US20250353857, Compound TIA03-024)
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617703BDBM50617703(CHEMBL5413223 | US20250353857, Compound TIA070)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617724BDBM50617724(CHEMBL5417420 | US20250353857, Compound TIA04-095)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617705BDBM50617705(CHEMBL5410595 | US20250353857, Compound TIA02-172)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617731BDBM50617731(CHEMBL5431583 | US20250353857, Compound KUL01-123)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617704BDBM50617704(CHEMBL5435576 | US20250353857, Compound TIA03-136)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617716BDBM50617716(CHEMBL5403333)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617717BDBM50617717(CHEMBL5410355 | US20250353857, Compound TIA04-009)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617707BDBM50617707(CHEMBL5429835 | US20250353857, Compound TIA02-130)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617722BDBM50617722(CHEMBL5406229 | US20250353857, Compound TIA04-093)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617711BDBM50617711(CHEMBL5399857 | US20250353857, Compound TIA03-014)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617733BDBM50617733(CHEMBL5410996 | US20250353857, Compound TIA072)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617719BDBM50617719(CHEMBL5397493 | US20250353857, Compound TIA03-066)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617708BDBM50617708(CHEMBL5394928 | US20250353857, Compound TIA02-132)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617715BDBM50617715(CHEMBL5428593 | US20250353857, Compound TIA02-166)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617710BDBM50617710(CHEMBL5408316 | US20250353857, Compound TIA03-106)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617725BDBM50617725(CHEMBL5404686 | US20250353857, Compound TIA04-051)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617723BDBM50617723(CHEMBL5401076 | US20250353857, Compound TIA04-049)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617713BDBM50617713(CHEMBL5414671 | US20250353857, Compound TIA03-080)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617714BDBM50617714(CHEMBL5428255 | US20250353857, Compound TIA02-164)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617709BDBM50617709(CHEMBL5400254 | US20250353857, Compound TIA02-134)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617718BDBM50617718(CHEMBL5399299 | US20250353857, Compound TIA03-108)
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617706BDBM50617706(CHEMBL5431785 | US20250353857, Compound TIA02-174)
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617732BDBM50617732(CHEMBL5403510 | US20250353857, Compound JH06-118)
Affinity DataIC50: 12nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617730BDBM50617730(CHEMBL5405639 | US20250353857, Compound KUL01-097)
Affinity DataIC50: 15nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617720BDBM50617720(CHEMBL5407395 | US20250353857, Compound TIA03-188)
Affinity DataKd:  17nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617731BDBM50617731(CHEMBL5431583 | US20250353857, Compound KUL01-123)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617735BDBM50617735(CHEMBL5439143 | US20250353857, Compound TIA098)
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617728BDBM50617728(CHEMBL5415149 | US20250353857, Compound TIA05-014)
Affinity DataKd:  36nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617720BDBM50617720(CHEMBL5407395 | US20250353857, Compound TIA03-188)
Affinity DataIC50: 40nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617735BDBM50617735(CHEMBL5439143 | US20250353857, Compound TIA098)
Affinity DataIC50: 43nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617726BDBM50617726(CHEMBL5416633 | US20250353857, Compound TIA04-063)
Affinity DataIC50: 53nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617712BDBM50617712(CHEMBL5430633 | US20250353857, Compound TIA03-078)
Affinity DataIC50: 61nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617729BDBM50617729(CHEMBL5440975 | US20250353857, Compound TIA04-067)
Affinity DataIC50: 68nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617725BDBM50617725(CHEMBL5404686 | US20250353857, Compound TIA04-051)
Affinity DataKd:  80nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617725BDBM50617725(CHEMBL5404686 | US20250353857, Compound TIA04-051)
Affinity DataIC50: 83nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617734BDBM50617734(CHEMBL1210237 | US20250353857, Compound TIA099)
Affinity DataIC50: 85nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617721BDBM50617721(CHEMBL5431736 | US20250353857, Compound TIA03-024)
Affinity DataIC50: 100nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177716BDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617728BDBM50617728(CHEMBL5415149 | US20250353857, Compound TIA05-014)
Affinity DataIC50: 106nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617703BDBM50617703(CHEMBL5413223 | US20250353857, Compound TIA070)
Affinity DataIC50: 109nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617727BDBM50617727(CHEMBL5424810 | US20250353857, Compound TIA04-053)
Affinity DataIC50: 130nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617720BDBM50617720(CHEMBL5407395 | US20250353857, Compound TIA03-188)
Affinity DataKd:  220nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617724BDBM50617724(CHEMBL5417420 | US20250353857, Compound TIA04-095)
Affinity DataIC50: 300nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Displayed 1 to 50 (of 56 total ) | Next | Last >>
Jump to: