Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50019712
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622141BDBM50622141(CHEMBL5433435)
Affinity DataIC50: 0.230nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622130BDBM50622130(CHEMBL5418139)
Affinity DataIC50: 0.380nMAssay Description:Inverse agonist activity at RORgammaT in human PBMC cells assessed as inhibition of Th17 polarization incubated for 48 hrsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622130BDBM50622130(CHEMBL5418139)
Affinity DataIC50: 0.400nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622136BDBM50622136(CHEMBL5424936)
Affinity DataIC50: 0.690nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 0.75nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622131BDBM50622131(CHEMBL5434019)
Affinity DataIC50: 0.820nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622138BDBM50622138(CHEMBL5409745)
Affinity DataIC50: 1.20nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622132BDBM50622132(CHEMBL5438268)
Affinity DataIC50: 1.5nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622138BDBM50622138(CHEMBL5409745)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622129BDBM50622129(CHEMBL5432066)
Affinity DataIC50: 1.60nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461084BDBM50461084(CHEMBL4225088)
Affinity DataIC50: 1.70nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622142BDBM50622142(CHEMBL5403342)
Affinity DataIC50: 1.80nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622135BDBM50622135(CHEMBL5433149)
Affinity DataIC50: 2.10nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622130BDBM50622130(CHEMBL5418139)
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622137BDBM50622137(CHEMBL5439193)
Affinity DataIC50: 2.20nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622134BDBM50622134(CHEMBL5420370)
Affinity DataIC50: 2.5nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622147BDBM50622147(CHEMBL5413912)
Affinity DataIC50: 3.40nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622140BDBM50622140(CHEMBL5435902)
Affinity DataIC50: 3.5nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622133BDBM50622133(CHEMBL5425785)
Affinity DataIC50: 3.80nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622139BDBM50622139(CHEMBL5401795)
Affinity DataIC50: 4.5nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622131BDBM50622131(CHEMBL5434019)
Affinity DataIC50: 4.5nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622143BDBM50622143(CHEMBL5394581)
Affinity DataIC50: 5.70nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622144BDBM50622144(CHEMBL5430108)
Affinity DataIC50: 9nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622148BDBM50622148(CHEMBL5415425)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622151BDBM50622151(CHEMBL5402128)
Affinity DataIC50: 17nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622146BDBM50622146(CHEMBL5401476)
Affinity DataIC50: 20nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622150BDBM50622150(CHEMBL5417316)
Affinity DataIC50: 20nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622145BDBM50622145(CHEMBL5399379)
Affinity DataIC50: 46nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622149BDBM50622149(CHEMBL5406949)
Affinity DataIC50: 57nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622141BDBM50622141(CHEMBL5433435)
Affinity DataIC50: 100nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed