Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50022397
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Binding affinity to recombinant Leishmania major NMT assessed as inhibition constantMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant Leishmania major NMT using GCGGSKVKPQPPQA[K-Biotin as peptide substrate incubated for 30 mins by scintillation luminescence...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant Leishmania major NMT using GCGGSKVKPQPPQA[K-Biotin as peptide substrate incubated for 30 mins by scintillation luminescence...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium vivax (strain Salvador I))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Binding affinity to Plasmodium vivax NMT assessed as inhibition constant using YnMyr-CoA as substrateMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity to Plasmodium falciparum NMT assessed as inhibition constant using GSNKSKPKDASQRRR-NH2 as peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human NMTMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human NMTMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human NMT assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NMTMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant Plasmodium falciparum NMT using 3H-myristoyl CoA as substrate preincubated for 15 mins followed by substrate addition and m...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium vivax (strain Salvador I))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant Plasmodium vivax NMTMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human NMTMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human NMTMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human NMTMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant his tagged Plasmodium falciparum NMT expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum NMT using 3H-myristoyl CoA as substrate preincubated for 15 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human NMT1More data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of human NMT2More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human NMT by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human NMTMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum NMTMore data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of human NMT2More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant N-terminal Plasmodium falciparum NMT expressed in Escherichia coli using peptide substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of human NMT1More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of human NMT1More data for this Ligand-Target Pair
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of human NMT1More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of recombinant N-terminal Plasmodium falciparum NMT expressed in Escherichia coli using peptide substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of recombinant N-terminal Plasmodium falciparum NMT expressed in Escherichia coli using peptide substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 5.63E+4nMAssay Description:Inhibition of human NMT2More data for this Ligand-Target Pair
Affinity DataIC50: 6.36E+4nMAssay Description:Inhibition of human NMT2More data for this Ligand-Target Pair
Affinity DataIC50: 6.41E+4nMAssay Description:Inhibition of human NMT2More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human NMT1More data for this Ligand-Target Pair
Affinity DataIC50: 7.32E+4nMAssay Description:Inhibition of human NMT1More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human NMT2More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 2.86E+5nMAssay Description:Inhibition of recombinant N-terminal his-6 tagged human NMT expressed in Escherichia coli BL21 (DE3)pLysS using peptide substrate preincubated for 5 ...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 6.56E+5nMAssay Description:Inhibition of recombinant N-terminal his-6 tagged human NMT expressed in Escherichia coli BL21 (DE3)pLysS using peptide substrate preincubated for 5 ...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
State University of Paraiba
Curated by ChEMBL
State University of Paraiba
Curated by ChEMBL
Affinity DataIC50: 6.56E+5nMAssay Description:Inhibition of recombinant N-terminal his-6 tagged human NMT expressed in Escherichia coli BL21 (DE3)pLysS using peptide substrate preincubated for 5 ...More data for this Ligand-Target Pair







3D Structure (crystal)












