Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50022322
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50535381(CHEMBL4591419)
Affinity DataEC50:  360nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50:  760nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650813(CHEMBL5633031)
Affinity DataEC50:  890nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650825(CHEMBL5632435)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650824(CHEMBL5633131)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650797(CHEMBL5634022)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650802(CHEMBL5632402)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650808(CHEMBL5632919)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650812(CHEMBL5632756)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650804(CHEMBL5631699)
Affinity DataEC50:  7.20E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650815(CHEMBL5632550)
Affinity DataEC50:  8.70E+3nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650820(CHEMBL5633307)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650819(CHEMBL5633508)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650818(CHEMBL5633547)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650817(CHEMBL5633610)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650823(CHEMBL5632959)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650822(CHEMBL5632426)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650821(CHEMBL5633304)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at LXR-beta (unknown origin) transfected in African green monkey CV-1 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at LXR-alpha (unknown origin) transfected in African green monkey CV-1 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650826(CHEMBL5631938)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at THR-beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPAR-gamma (unknown origin) transfected in HEK293 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPAR-alpha (unknown origin) transfected in human HepG2 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PXR (unknown origin) transfected in African green monkey CV-1 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650803(CHEMBL5633102)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650801(CHEMBL5631840)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650807(CHEMBL5632708)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650806(CHEMBL5631537)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650805(CHEMBL5633583)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650811(CHEMBL5632225)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650810(CHEMBL5633530)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650809(CHEMBL5633465)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650816(CHEMBL5632904)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650800(CHEMBL5634017)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650799(CHEMBL5633593)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBile acid receptor(Human)TBA
LigandPNGBDBM50650798(CHEMBL5633335)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR LBD (unknown origin) using fluorescein-SRC2-2 as substrate incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)TBA
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) transfected in African green monkey CV-1 cells incubated for 18 hrs by luciferase report...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetEstrogen receptor beta(Human)TBA
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ER-beta (unknown origin) transfected in African green monkey CV-1 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetEstrogen receptor(Human)TBA
LigandPNGBDBM50650814(CHEMBL5633111)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ER-alpha (unknown origin) transfected in African green monkey CV-1 cells incubated for 18 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed