Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50021231
LigandPNGBDBM50011178(CHEMBL3260316)
Affinity DataIC50: 0.174nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50569950(CHEMBL4868614)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50569950(CHEMBL4868614)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human EGFR L861Q mutant by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50453428(CHEMBL4205098)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal 6His-tagged human NAMPT (unknown origin) expressed in Escherichia coli Rosetta (DE) cells incubated for 1 hr by bradford ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50638510(CHEMBL3586462)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50448621(CHEMBL3127521)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of N-terminal 6His-tagged human NAMPT (unknown origin) expressed in Escherichia coli Rosetta (DE) cells incubated for 1 hr by bradford ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50448621(CHEMBL3127521)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate pre-treated for 15 mins followed by substrate addition incubated for 60 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50638507(CHEMBL4217940)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of N-terminal 6His-tagged human NAMPT (unknown origin) expressed in Escherichia coli Rosetta (DE) cells incubated for 1 hr by bradford ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638509(CHEMBL5543015)
Affinity DataIC50: 14nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50: 31nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638508(CHEMBL5542641)
Affinity DataIC50: 42nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50241442(CHEMBL4092869)
Affinity DataIC50: 116nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50569950(CHEMBL4868614)
Affinity DataIC50: 152nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50606267(CHEMBL5202802)
Affinity DataIC50: 183nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638512(CHEMBL5557739)
Affinity DataIC50: 490nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50241442(CHEMBL4092869)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638511(CHEMBL5557597)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed