Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50022306
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650594(CHEMBL5629885)
Affinity DataKd:  17nMAssay Description:Binding affinity to Mycobacterium tuberculosis DHFR assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650593(CHEMBL5081820)
Affinity DataKd:  640nMAssay Description:Binding affinity to Mycobacterium tuberculosis DHFR assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650586(CHEMBL5630190)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650584(CHEMBL5624869)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650590(CHEMBL5630227)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650589(CHEMBL5624848)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50295339(CHEMBL4162042)
Affinity DataKd:  6.30E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650592(CHEMBL5629913)
Affinity DataKd:  7.10E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650591(CHEMBL5630734)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650588(CHEMBL4800208)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650585(CHEMBL4096606)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50650587(CHEMBL4797728)
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM228827(3-Cyclopentyl-1-(pyrrolidin-1-yl)propan-1-one (1))
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM222349(CYP144A1 ligand, 4)
Affinity DataIC50: 6.74E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed