Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50022329
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  62nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi:  98nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProthrombin(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  100nMAssay Description:Inhibition of human thrombin incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlasminogen(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  106nMAssay Description:Inhibition of human plasmin using S-2366 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650896(CHEMBL5633098)
Affinity DataKi:  147nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650897(CHEMBL5631608)
Affinity DataKi:  248nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650901(CHEMBL5632608)
Affinity DataKi:  506nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650902(CHEMBL5632532)
Affinity DataKi:  529nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650891(CHEMBL5632673)
Affinity DataKi:  802nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProthrombin(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi:  895nMAssay Description:Inhibition of human thrombin incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650895(CHEMBL5632365)
Affinity DataKi:  1.48E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlasminogen(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of human plasmin using S-2366 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650900(CHEMBL5633045)
Affinity DataKi:  2.23E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650892(CHEMBL5632243)
Affinity DataKi:  3.61E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650894(CHEMBL5631662)
Affinity DataKi:  3.95E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650889(CHEMBL5632581)
Affinity DataKi:  4.98E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650893(CHEMBL5631607)
Affinity DataKi:  5.19E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50180541(4-guanidinophenyl 6-(chloromethyl)-2-oxo-2H-chrome...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650890(CHEMBL5632873)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XI(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  8.64E+3nMAssay Description:Inhibition of human FXIa using S-2366 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of human Fxa using pNAPEP-8503 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XI(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human FXIa using S-2366 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTissue-type plasminogen activator(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator using ppNAPEP-9101 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetChymotrypsinogen A(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of bovine alpha-chymotrypsin using N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetChymotrypsinogen A(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of bovine alpha-chymotrypsin using N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTissue-type plasminogen activator(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator using ppNAPEP-9101 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650899(CHEMBL5633706)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human Fxa using pNAPEP-8503 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650903(CHEMBL5633444)
Affinity DataIC50: 3.87E+5nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM14320(CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL537204 | CHEMBL20...)
Affinity DataIC50: 2.38E+6nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650904(CHEMBL5631353)
Affinity DataIC50: 2.76E+6nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50053620(1N-amino(immino)methylaniline | 1-phenylguanidine ...)
Affinity DataIC50: 1.69E+7nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed