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Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 50021233
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638529(CHEMBL5555176)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638564(CHEMBL5426437)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638563(CHEMBL5430416)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured for 20 mins by absor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638521(CHEMBL5434603)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638565(CHEMBL5408010)
Affinity DataIC50: 1nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638532(CHEMBL5567981)
Affinity DataIC50: 2nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638543(CHEMBL5430590)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638531(CHEMBL5555631)
Affinity DataIC50: 6nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638530(CHEMBL5542984)
Affinity DataIC50: 6nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate pre-treated for 10 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50610795(CHEMBL5289108)
Affinity DataKi:  7nMAssay Description:Binding affinity to mushroom tyrosinase assessed as binding constant by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638527(CHEMBL5424468)
Affinity DataIC50: 10nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638563(CHEMBL5430416)
Affinity DataKi:  10nMAssay Description:Binding affinity to mushroom tyrosinase assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638567(CHEMBL5414043)
Affinity DataIC50: 14nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638526(CHEMBL5563258)
Affinity DataIC50: 15nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638514(CHEMBL5542405)
Affinity DataKi:  18nMAssay Description:Binding affinity to mushroom tyrosinase assessed as binding constant by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638568(CHEMBL5427541)
Affinity DataIC50: 19nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50569812(CHEMBL4869068)
Affinity DataIC50: 20nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638544(CHEMBL5430008)
Affinity DataIC50: 24nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50569806(CHEMBL4865646)
Affinity DataIC50: 30nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638534(CHEMBL5556404)
Affinity DataIC50: 33nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638536(CHEMBL5558138)
Affinity DataIC50: 34nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638537(CHEMBL5563618)
Affinity DataIC50: 35nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638533(CHEMBL5558770)
Affinity DataIC50: 36nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638523(CHEMBL5560484)
Affinity DataIC50: 50nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50608983(CHEMBL5271552)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50569799(CHEMBL4852561)
Affinity DataIC50: 60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50569801(CHEMBL4867662)
Affinity DataIC50: 70nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638535(CHEMBL5559903)
Affinity DataIC50: 72nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638545(CHEMBL5427085)
Affinity DataIC50: 80nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638514(CHEMBL5542405)
Affinity DataIC50: 98nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638566(CHEMBL5422809)
Affinity DataKi:  100nMAssay Description:Binding affinity to mushroom tyrosinase assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638515(CHEMBL5567857)
Affinity DataIC50: 110nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638556(CHEMBL5401668)
Affinity DataIC50: 110nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638524(CHEMBL5559951)
Affinity DataIC50: 113nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638581(CHEMBL5403021)
Affinity DataIC50: 120nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate measured for 15 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638528(CHEMBL5559662)
Affinity DataIC50: 122nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638516(CHEMBL5532371)
Affinity DataIC50: 124nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638579(CHEMBL5411074)
Affinity DataIC50: 140nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate measured for 15 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638517(CHEMBL5563608)
Affinity DataIC50: 142nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638538(CHEMBL5542955)
Affinity DataIC50: 142nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosinase(Human)TBA
LigandPNGBDBM50638585(CHEMBL5559732)
Affinity DataIC50: 220nMAssay Description:Competitive inhibition of His-tagged human tyrosinase expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosinase(Human)TBA
LigandPNGBDBM50638584(CHEMBL5542520)
Affinity DataIC50: 220nMAssay Description:Competitive inhibition of His-tagged human tyrosinase expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosinase(Human)TBA
LigandPNGBDBM50638583(CHEMBL5542638)
Affinity DataIC50: 220nMAssay Description:Competitive inhibition of His-tagged human tyrosinase expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosinase(Human)TBA
LigandPNGBDBM50638582(CHEMBL5555785)
Affinity DataIC50: 220nMAssay Description:Competitive inhibition of His-tagged human tyrosinase expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50569798(CHEMBL4848104)
Affinity DataIC50: 230nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition incubated for 10 mins by absorban...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638525(CHEMBL5566933)
Affinity DataIC50: 240nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50638580(CHEMBL5395049)
Affinity DataIC50: 250nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate measured for 15 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50608984(CHEMBL5277342)
Affinity DataIC50: 300nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50608993(CHEMBL5291410)
Affinity DataIC50: 520nMAssay Description:Inhibition of mushroom tyrosinase incubated for 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
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