Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50020200
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627347BDBM50627347(CHEMBL5404655)
Affinity DataEC50:  1nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627345BDBM50627345(CHEMBL5440962)
Affinity DataEC50:  1nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627338BDBM50627338(CHEMBL5420155)
Affinity DataEC50:  1nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627357BDBM50627357(CHEMBL5415989)
Affinity DataEC50:  4nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627350BDBM50627350(CHEMBL5393952)
Affinity DataEC50:  5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627356BDBM50627356(CHEMBL5399999)
Affinity DataEC50:  7nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627346BDBM50627346(CHEMBL5396362)
Affinity DataEC50:  9nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604481BDBM50604481(CHEMBL5174660)
Affinity DataEC50:  10nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627337BDBM50627337(CHEMBL5426794)
Affinity DataEC50:  18nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627352BDBM50627352(CHEMBL5396536)
Affinity DataEC50:  20nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627344BDBM50627344(CHEMBL5425041)
Affinity DataEC50:  20nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627342BDBM50627342(CHEMBL5426413)
Affinity DataEC50:  20nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627351BDBM50627351(CHEMBL5416408)
Affinity DataEC50:  60nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627355BDBM50627355(CHEMBL5403509)
Affinity DataEC50:  60nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627359BDBM50627359(CHEMBL5400005)
Affinity DataEC50:  90nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627360BDBM50627360(CHEMBL5405814)
Affinity DataEC50:  150nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627343BDBM50627343(CHEMBL5407664)
Affinity DataEC50:  270nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627358BDBM50627358(CHEMBL5434110)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627341BDBM50627341(CHEMBL5402163)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627348BDBM50627348(CHEMBL5407209)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627349BDBM50627349(CHEMBL5433006)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627339BDBM50627339(CHEMBL5401068)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627340BDBM50627340(CHEMBL5414952)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627353BDBM50627353(CHEMBL5427743)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Mersana Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627354BDBM50627354(CHEMBL5425842)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed