Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50019403
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24567BDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1.60nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346613BDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 490nMAssay Description:Inhibition of Pancreatic lipase (unknown origin) using 4-MUO as fluorescent substrate preincubated for 3 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15236BDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 1.34E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.53E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560416BDBM50560416(CHEMBL4641560)
Affinity DataIC50: 1.63E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618931BDBM50618931(CHEMBL5410259)
Affinity DataKi:  1.67E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase assessed as inhibition of PL-mediated DDAO-ol hydrolysis by measuring inhibition co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560416BDBM50560416(CHEMBL4641560)
Affinity DataKi:  1.70E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase assessed as inhibition of PL-mediated DDAO-ol hydrolysis by measuring inhibition co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618931BDBM50618931(CHEMBL5410259)
Affinity DataIC50: 1.86E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618932BDBM50618932(CHEMBL1631675)
Affinity DataIC50: 2.13E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022832BDBM50022832(Rafoxanide)
Affinity DataIC50: 2.52E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179008BDBM50179008(sanggenon C | CHEMBL204813)
Affinity DataIC50: 3.28E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618929BDBM50618929(CHEMBL5423733)
Affinity DataIC50: 4.27E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618927BDBM50618927(CHEMBL5419885)
Affinity DataIC50: 5.99E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618926BDBM50618926(CHEMBL5413231)
Affinity DataIC50: 6.27E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618911BDBM50618911(CHEMBL5405185)
Affinity DataIC50: 6.75E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618915BDBM50618915(CHEMBL5439220)
Affinity DataIC50: 9.24E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618910BDBM50618910(CHEMBL5402667)
Affinity DataIC50: 9.96E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618925BDBM50618925(CHEMBL5399755)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618919BDBM50618919(CHEMBL5420710)
Affinity DataIC50: 1.05E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618918BDBM50618918(CHEMBL5430137)
Affinity DataIC50: 1.10E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618912BDBM50618912(CHEMBL5436175)
Affinity DataIC50: 1.14E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618913BDBM50618913(CHEMBL5396102)
Affinity DataIC50: 1.20E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618928BDBM50618928(CHEMBL5428235)
Affinity DataIC50: 1.24E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618930BDBM50618930(CHEMBL5412428)
Affinity DataIC50: 1.24E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618917BDBM50618917(CHEMBL5404043)
Affinity DataIC50: 1.50E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618923BDBM50618923(CHEMBL5409756)
Affinity DataIC50: 1.58E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618921BDBM50618921(CHEMBL5418104)
Affinity DataIC50: 1.67E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618922BDBM50618922(CHEMBL5404594)
Affinity DataIC50: 1.83E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618908BDBM50618908(CHEMBL5409828)
Affinity DataIC50: 1.91E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618909BDBM50618909(CHEMBL5432097)
Affinity DataIC50: 2.04E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618916BDBM50618916(CHEMBL5412841)
Affinity DataIC50: 2.37E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618924BDBM50618924(CHEMBL5413833)
Affinity DataIC50: 2.63E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618920BDBM50618920(CHEMBL5432795)
Affinity DataIC50: 2.74E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618914BDBM50618914(CHEMBL5415926)
Affinity DataIC50: 3.27E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618907BDBM50618907(OSALMID | Osalmid | Osalmide | Osalmida | L-1718 |...)
Affinity DataIC50: 5.00E+5nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed