Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50022341
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 0.00900nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of EGFR del19 mutant (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311470BDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of EGFR del19 mutant (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311470BDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 0.109nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 0.190nMAssay Description:Irreversible covalent inhibition of recombinant full length EGFR (unknown origin) incubated for 4 hrs in presence of ATP by ADP-Glo reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of EGFR C797S mutant (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311470BDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of EGFR C797S mutant (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 0.830nMAssay Description:Irreversible covalent inhibition of recombinant full length EGFR (unknown origin) measured immediately in presence of ATP by ADP-Glo reagent based as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 112499BDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311470BDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311470BDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651048BDBM50651048(CHEMBL5631574)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651052BDBM50651052(CHEMBL5632632)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651045BDBM50651045(CHEMBL5633067)
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system incubated for 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651056BDBM50651056(CHEMBL5631426)
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651047BDBM50651047(CHEMBL5631951)
Affinity DataIC50: 37nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651063BDBM50651063(CHEMBL5633818)
Affinity DataIC50: 37nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651048BDBM50651048(CHEMBL5631574)
Affinity DataIC50: 41nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system incubated for 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651066BDBM50651066(CHEMBL5631269)
Affinity DataIC50: 54nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651047BDBM50651047(CHEMBL5631951)
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system incubated for 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651067BDBM50651067(CHEMBL5633094)
Affinity DataIC50: 97nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651057BDBM50651057(CHEMBL5633106)
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651060BDBM50651060(CHEMBL5631782)
Affinity DataIC50: 122nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651046BDBM50651046(CHEMBL5633759)
Affinity DataIC50: 142nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651046BDBM50651046(CHEMBL5633759)
Affinity DataIC50: 171nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system incubated for 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651058BDBM50651058(CHEMBL5631902)
Affinity DataIC50: 186nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651062BDBM50651062(CHEMBL5632485)
Affinity DataIC50: 193nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651055BDBM50651055(CHEMBL5632295)
Affinity DataIC50: 267nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651061BDBM50651061(CHEMBL5632548)
Affinity DataIC50: 560nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651054BDBM50651054(CHEMBL5631882)
Affinity DataIC50: 594nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651064BDBM50651064(CHEMBL5632830)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651053BDBM50651053(CHEMBL5632582)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651059BDBM50651059(CHEMBL5632007)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651049BDBM50651049(CHEMBL5634013)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651065BDBM50651065(CHEMBL5633509)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651051BDBM50651051(CHEMBL5633775)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
National University of Singapore

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651050BDBM50651050(CHEMBL5631513)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (668 to end residues) expressed in baculovirus infected Sf9 cells incubated for 1 hrs in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed