Compile Data Set for Download or QSAR
Report error Found 113 Enz. Inhib. hit(s) with all data for entry = 50019425
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619090(CHEMBL5426012)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619089(CHEMBL5405339)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619100(CHEMBL5416899)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619100(CHEMBL5416899)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619091(CHEMBL5403724)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619098(CHEMBL5416582)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619097(CHEMBL5415010)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619096(CHEMBL5423260)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619096(CHEMBL5423260)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619099(CHEMBL5407403)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619089(CHEMBL5405339)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619092(CHEMBL5404274)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619098(CHEMBL5416582)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619094(CHEMBL5419235)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619095(CHEMBL5413519)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619090(CHEMBL5426012)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50514549(CHEMBL4548515)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619101(CHEMBL5394355)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619095(CHEMBL5413519)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619099(CHEMBL5407403)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619089(CHEMBL5405339)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619091(CHEMBL5403724)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619098(CHEMBL5416582)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619100(CHEMBL5416899)
Affinity DataEC50:  9.40nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50514545(CHEMBL4435280)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619090(CHEMBL5426012)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619100(CHEMBL5416899)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-U69593 from human KOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619101(CHEMBL5394355)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619094(CHEMBL5419235)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619099(CHEMBL5407403)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619092(CHEMBL5404274)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619096(CHEMBL5423260)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-U69593 from human KOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619095(CHEMBL5413519)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619089(CHEMBL5405339)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619094(CHEMBL5419235)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619089(CHEMBL5405339)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-U69593 from human KOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619100(CHEMBL5416899)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619091(CHEMBL5403724)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619090(CHEMBL5426012)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619098(CHEMBL5416582)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-U69593 from human KOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619092(CHEMBL5404274)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619097(CHEMBL5415010)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-U69593 from human KOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619097(CHEMBL5415010)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619097(CHEMBL5415010)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619098(CHEMBL5416582)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619099(CHEMBL5407403)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50514540(CHEMBL4439997)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619096(CHEMBL5423260)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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