Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50020452
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 57nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM18070(5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)me...)
Affinity DataIC50: 65nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630009(CHEMBL5409950)
Affinity DataIC50: 88nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630008(CHEMBL5425512)
Affinity DataIC50: 150nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630007(CHEMBL5407162)
Affinity DataIC50: 164nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630003(CHEMBL5435092)
Affinity DataIC50: 191nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630006(CHEMBL5405387)
Affinity DataIC50: 230nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630005(CHEMBL5411835)
Affinity DataIC50: 270nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630004(CHEMBL5402769)
Affinity DataIC50: 370nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630001(CHEMBL5393757)
Affinity DataIC50: 681nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630002(CHEMBL5413005)
Affinity DataIC50: 701nMAssay Description:Inhibition of Escherichia coli DHFR incubated for 10 mins in presence of NADPH by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed