Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50022427
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50652129(CHEMBL5646469)
Affinity DataIC50: 115nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Human)TBA
LigandPNGBDBM50652129(CHEMBL5646469)
Affinity DataIC50: 421nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins by E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50652130(CHEMBL5641542)
Affinity DataIC50: 762nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652129(CHEMBL5646469)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2B expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2B expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Human)TBA
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50062599(CHEMBL807 | Namenda | 3,5-Dimethyl-adamantan-1-yla...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2A expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Human)TBA
LigandPNGBDBM50652130(CHEMBL5641542)
Affinity DataIC50: 5.08E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins by E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50062599(CHEMBL807 | Namenda | 3,5-Dimethyl-adamantan-1-yla...)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2B expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 5.74E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2A expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652130(CHEMBL5641542)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2A expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652129(CHEMBL5646469)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2A expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652130(CHEMBL5641542)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2B expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed