Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022444
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649863(CHEMBL5624606)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant EGFR L858R/T790M/C797S mutant (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649863(CHEMBL5624606)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant EGFR Del19/T790M/C797S mutant (unknown origin) in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652322(CHEMBL5589715)
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 44nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant EGFR Del19/T790M/C797S mutant (unknown origin) preincubated for 10 mins followed by substrate and ATP addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50652322(CHEMBL5589715)
Affinity DataIC50: 113nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 235nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)