Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 50020476
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.00500nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.0100nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.0140nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.0150nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.0280nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630282(CHEMBL5407887)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630280(CHEMBL5433813)
Affinity DataEC50:  0.0900nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630282(CHEMBL5407887)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of TNFalpha release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630278(CHEMBL5432710)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  0.310nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630278(CHEMBL5432710)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630276(CHEMBL5428754)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630282(CHEMBL5407887)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630276(CHEMBL5428754)
Affinity DataEC50:  0.480nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630280(CHEMBL5433813)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630282(CHEMBL5407887)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630282(CHEMBL5407887)
Affinity DataEC50:  0.680nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  0.760nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630277(CHEMBL507938)
Affinity DataEC50:  0.930nMAssay Description:Agonist activity at human TLR4 in human HEK-Blue hTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630282(CHEMBL5407887)
Affinity DataEC50:  0.970nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  0.990nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630280(CHEMBL5433813)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630276(CHEMBL5428754)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630283(CHEMBL5423611)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of TNFalpha release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630280(CHEMBL5433813)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630278(CHEMBL5432710)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630278(CHEMBL5432710)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630280(CHEMBL5433813)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630276(CHEMBL5428754)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630281(CHEMBL5407900)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of TNFalpha release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630276(CHEMBL5428754)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
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