Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50020378
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629416(CHEMBL5439905)
Affinity DataEC50:  18nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629415(CHEMBL5405415)
Affinity DataEC50:  39nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629417(CHEMBL5424404)
Affinity DataEC50:  44nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629421(CHEMBL5396405)
Affinity DataEC50:  59nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629414(CHEMBL5419915)
Affinity DataEC50:  62nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629429(CHEMBL5423654)
Affinity DataEC50:  69nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629420(CHEMBL5424893)
Affinity DataEC50:  84nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629422(CHEMBL5433548)
Affinity DataEC50:  107nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629419(CHEMBL5436292)
Affinity DataEC50:  168nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629430(CHEMBL5408883)
Affinity DataEC50:  176nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629428(CHEMBL5393892)
Affinity DataEC50:  199nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629431(CHEMBL5434429)
Affinity DataEC50:  209nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629423(CHEMBL5414036)
Affinity DataEC50:  231nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629426(CHEMBL5400489)
Affinity DataEC50:  232nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629424(CHEMBL5406767)
Affinity DataEC50:  275nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629418(CHEMBL5434936)
Affinity DataEC50:  344nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629435(CHEMBL5396643)
Affinity DataEC50:  485nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629425(CHEMBL5439729)
Affinity DataEC50:  540nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  616nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629433(CHEMBL5433089)
Affinity DataEC50:  840nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629427(CHEMBL5436371)
Affinity DataEC50:  1.31E+3nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629434(CHEMBL5399142)
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629436(CHEMBL5414341)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629432(CHEMBL5408203)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629438(CHEMBL5436701)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629439(CHEMBL5409098)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629437(CHEMBL5418029)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed