Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50020387
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629518(CHEMBL5412259 | US20250282782, Compound 222)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629514(CHEMBL5402623 | US20250282782, Compound 186)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629515(CHEMBL5402432 | US20250282782, Compound 192)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629513(CHEMBL5397998 | US20250282782, Compound 183)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629516(CHEMBL5411170 | US20250282782, Compound 193)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629517(CHEMBL5423545 | US20250282782, Compound 208)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed