Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50022453
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652470BDBM50652470(CHEMBL5639852)
Affinity DataEC50:  13nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652453BDBM50652453(CHEMBL5646836)
Affinity DataEC50:  22nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652463BDBM50652463(CHEMBL5641800)
Affinity DataEC50:  23nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652462BDBM50652462(CHEMBL5639167)
Affinity DataEC50:  26nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652464BDBM50652464(CHEMBL5646884)
Affinity DataEC50:  28nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652465BDBM50652465(CHEMBL5639480)
Affinity DataEC50:  34nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652466BDBM50652466(CHEMBL5639313)
Affinity DataEC50:  48nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652459BDBM50652459(CHEMBL5641840)
Affinity DataEC50:  50nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652469BDBM50652469(CHEMBL5639295)
Affinity DataEC50:  59nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652451BDBM50652451(CHEMBL5639861)
Affinity DataEC50:  96nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652456BDBM50652456(CHEMBL5647032)
Affinity DataEC50:  136nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652448BDBM50652448(CHEMBL5646849)
Affinity DataEC50:  180nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652452BDBM50652452(CHEMBL5647159)
Affinity DataEC50:  220nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652458BDBM50652458(CHEMBL5639293)
Affinity DataEC50:  234nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652450BDBM50652450(CHEMBL5641758)
Affinity DataEC50:  460nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652436BDBM50652436(CHEMBL5641625)
Affinity DataEC50:  696nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652457BDBM50652457(CHEMBL5647467)
Affinity DataEC50:  859nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50294528BDBM50294528(methyl orsellinate | methyl 2,4-dihydroxy-6-methyl...)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652468BDBM50652468(CHEMBL5647581)
Affinity DataEC50:  1.14E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652449BDBM50652449(CHEMBL5639305)
Affinity DataEC50:  1.23E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652447BDBM50652447(CHEMBL5641646)
Affinity DataEC50:  2.92E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652437BDBM50652437(CHEMBL5639574)
Affinity DataEC50:  4.08E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30705BDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataEC50:  9.90E+3nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652455BDBM50652455(CHEMBL5641717)
Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652438BDBM50652438(CHEMBL5647410)
Affinity DataEC50:  2.94E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652461BDBM50652461(CHEMBL5647453)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652460BDBM50652460(CHEMBL5646489)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652467BDBM50652467(CHEMBL5647208)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652435BDBM50652435(CHEMBL5639308)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652439BDBM50652439(CHEMBL5647160)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652443BDBM50652443(CHEMBL5639709)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652442BDBM50652442(CHEMBL5647325)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652441BDBM50652441(CHEMBL5646903)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652440BDBM50652440(CHEMBL5646642)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652446BDBM50652446(CHEMBL5639268)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652445BDBM50652445(CHEMBL5646503)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652444BDBM50652444(CHEMBL5639384)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652454BDBM50652454(CHEMBL5639438)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Full length wild type mouse RyR2 expressed in Flp-In-T-REx-293 cells assessed as increase in Ca2+ release endoplasmic reticulum by flex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed