Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019467
TargetTyrosine-protein kinase SYK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM212271(US9504684, Ex.-2 | 6-(6-aminopyrazin-2-yl)-N-(4-(4...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50015448(CHEMBL3265032)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human SYK assessed as tryptase release measured after 30 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of SYK-mediated human Mast cell degranulation assessed as tryptase release measured after 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of GST-tagged human SYK expressed in Sf21 cells measured after 1 hrs in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50619504(CHEMBL5407054)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human SYK at Py+3 pocketMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed