Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50020995
LigandPNGBDBM50635854((+/-)-Kavain | CHEMBL1482039)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MAO-A (unknown origin) measured by MAO-GloTM methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50594947(VAFIDEMSTAT | Vafidemstat | ORY-2001)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant LSD1 using H3K4me2 as peptide substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50568519(CHEMBL4875187)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant LSD1 using H3K4me2 as peptide substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50153586(CHEMBL3775474 | US10053456, 120 | US9718814, 71 | ...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of N-terminal His-tagged LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM425083(US10519118, Example 158 | N-((S)-5-((1R,2S)-2-(4- ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetDCN1-like protein 1(Human)TBA
LigandPNGBDBM50621125(CHEMBL5315233)
Affinity DataIC50: 11nMAssay Description:Inhibition of DCN1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 13nMAssay Description:Inhibition of LSD1 (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50618605(Incb 59872 | Incb-059872 | INCB059872 | INCB-05987...)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal His-tagged LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50635852(CHEMBL5558839)
Affinity DataIC50: 43nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50594960(CHEMBL5182796)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant LSD1 by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635853(CHEMBL5562925)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-tagged LSD1 (171 to 852 residues) (unknown origin) expressed in Escherichia coli using ART(mK)QTARKSTGGKAPRKQLAGGK-Bioti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50621125(CHEMBL5315233)
Affinity DataIC50: 288nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 570nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 600nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50158869(CHEMBL3786182 | US10836743, Compound GSK-2879552 |...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635852(CHEMBL5558839)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50635854((+/-)-Kavain | CHEMBL1482039)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of human recombinant LSD1 incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50113851(Tranylcypromine,(+) | TRANYLCYPROMINE | US8609708,...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetDCN1-like protein 1(Human)TBA
LigandPNGBDBM50635855(CHEMBL5272530)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of DCN1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed