Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50021593
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642339(CHEMBL5568904)
Affinity DataIC50: 890nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642344(CHEMBL5567170)
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642337(CHEMBL5595315)
Affinity DataIC50: 2.67E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642345(CHEMBL5571821)
Affinity DataIC50: 2.85E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642338(CHEMBL5569389)
Affinity DataIC50: 3.57E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642340(CHEMBL5564082)
Affinity DataIC50: 3.71E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642325(CHEMBL5570505)
Affinity DataIC50: 4.27E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642343(CHEMBL5574125)
Affinity DataIC50: 4.99E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642336(CHEMBL5567095)
Affinity DataIC50: 5.17E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642326(CHEMBL5571011)
Affinity DataIC50: 5.82E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642327(CHEMBL5574735)
Affinity DataIC50: 6.27E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642335(CHEMBL5568984)
Affinity DataIC50: 6.64E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642334(CHEMBL5566799)
Affinity DataIC50: 6.65E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642333(CHEMBL5563884)
Affinity DataIC50: 6.93E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642342(CHEMBL5569132)
Affinity DataIC50: 7.31E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642328(CHEMBL5565546)
Affinity DataIC50: 8.77E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642341(CHEMBL5571410)
Affinity DataIC50: 9.24E+3nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642329(CHEMBL5570321)
Affinity DataIC50: 1.16E+4nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642330(CHEMBL5591721)
Affinity DataIC50: 1.35E+4nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642332(CHEMBL5595380)
Affinity DataIC50: 1.47E+4nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50642331(CHEMBL5566319)
Affinity DataIC50: 1.48E+4nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50236230(ursodeoxy cholic acid | 2-((R)-4-((3R,5S,7S,8R,9S,...)
Affinity DataIC50: 6.82E+4nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBile acid receptor(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50118070((Z)-Gugglesterone | Guggulsterone)
Affinity DataIC50: 7.44E+4nMAssay Description:Antagonist activity against human FXR transfected in HEK293T cells co-transfected with pCDNA-hFXR and pRL-TK incubated for 24 hrs by dual-luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed