Compile Data Set for Download or QSAR
Report error Found 163 Enz. Inhib. hit(s) with all data for entry = 50021125
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM509947(US11124497, Compound 639 (Isomer 1) | US11524940, ...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of SARS-CoV-2 3-chymotrypsin-like protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of SARS-CoV-2 Main protease using peptide substrate assessed as fluorescence of cleaves substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637248(CHEMBL5276490)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637247(CHEMBL5275166)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50594616(CHEMBL5170425)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637274(CHEMBL5556435)
Affinity DataIC50: 10nMAssay Description:Inhibition of SARS-CoV-2 3CLp by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50627843(CHEMBL5288416)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637273(CHEMBL5564896)
Affinity DataIC50: 10nMAssay Description:Inhibition of SARS-CoV-2 3CLp by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637276(CHEMBL5557111)
Affinity DataIC50: 12nMAssay Description:Inhibition of SARS-CoV-2 3CLp by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50594612(CHEMBL5185160)
Affinity DataIC50: 13nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637277(CHEMBL5561775)
Affinity DataIC50: 14nMAssay Description:Inhibition of SARS-CoV-2 3CLp by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50598463(CHEMBL5195325)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637228(CHEMBL5555618)
Affinity DataIC50: 15nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637229(CHEMBL5562461)
Affinity DataIC50: 17nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637308(CHEMBL5567822)
Affinity DataIC50: 18nMAssay Description:Inhibition of SARS-CoV-2 recombinant main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637275(CHEMBL5561918)
Affinity DataIC50: 18nMAssay Description:Inhibition of SARS-CoV-2 3CLp by mass spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637246(CHEMBL5564996)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50627844(CHEMBL5267952)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLp using fluorogenic substrate by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637240(CHEMBL5555689)
Affinity DataIC50: 20nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637305(CHEMBL5564566)
Affinity DataIC50: 24nMAssay Description:Inhibition of SARS-CoV-2 recombinant main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637301(CHEMBL5559623)
Affinity DataIC50: 25nMAssay Description:Inhibition of SARS-CoV-2 recombinant main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50617129(CHEMBL5076204)
Affinity DataIC50: 30nMAssay Description:Inhibition of 2019-nCoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM61971(KSC-6-175 | cid_22416237 | 5-bromanyl-2-phenyl-1,2...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant SARS-CoV2 6xHis-tag-Main protease containing modified HRV-3C expressed in Escherichia coli using Mca-AVLQSGFR-K(Dnp)K pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50594591(CHEMBL5195764)
Affinity DataIC50: 35nMAssay Description:Inhibition of SARS-CoV-2 3CLp by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637307(CHEMBL5542616)
Affinity DataIC50: 36nMAssay Description:Inhibition of SARS-CoV-2 recombinant main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637306(CHEMBL5561093)
Affinity DataIC50: 37nMAssay Description:Inhibition of SARS-CoV-2 recombinant main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM659295(US20240092759, Compound 29)
Affinity DataIC50: 37nMAssay Description:Inhibition of SARS-CoV-2 recombinant main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM420297(med.21724, Compound 62 | peptidomimetic aldehydes ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of 2019-nCoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637245(CHEMBL5517978)
Affinity DataIC50: 50nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637231(CHEMBL5532217)
Affinity DataIC50: 51nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM420296(med.21724, Compound 61 | peptidomimetic aldehydes ...)
Affinity DataIC50: 53nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637230(CHEMBL5560375)
Affinity DataIC50: 54nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM496896(science.abl4784, 2 | WO2021250648, Example 4 | US1...)
Affinity DataIC50: 57nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM682832(US20240208970, Compound 39 | 7-(isoquinolin-4-yl)-...)
Affinity DataIC50: 71nMAssay Description:Inhibition of SARS-CoV-2 Main protease assessed as hydrolysis of quenched fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of SARS-CoV-2 Main protease assessed as hydrolysis of quenched fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM510005(Jun9-88-6R)
Affinity DataIC50: 80nMAssay Description:Inhibition of SARS-CoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM597988(US11612603, Compound 1)
Affinity DataIC50: 93nMAssay Description:Inhibition of 2019-nCoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637317(CHEMBL5556407)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637316(CHEMBL5532034)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637315(CHEMBL5565024)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637314(CHEMBL5542639)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50637318(CHEMBL5556937)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50129950(EBSELEN)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant SARS-CoV2 6xHis-tag-Main protease containing modified HRV-3C expressed in Escherichia coli using Mca-AVLQSGFR-K(Dnp)K pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM585220((E)-3-(4-((4-((6-chloro-2-methyl-2H-indazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM585230((E)-7-(4-((4-((6-chloro-2-methyl-2H-indazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM585229((E)-6-(4-((4-((6-chloro-2-methyl-2H-indazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM585228((E)-5-(4-((4-((6-chloro-2-methyl-2H-indazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM585227((E)-4-(4-((4-((6-chloro-2-methyl-2H-indazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM585237(US11530195, Compound 18)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 3CLpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Displayed 1 to 50 (of 163 total ) | Next | Last >>
Jump to: