Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50021602
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642451BDBM50642451(CHEMBL586281)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18512BDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110770BDBM50110770(5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataIC50: 8.17E+3nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642448BDBM50642448(CHEMBL5575210)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642446BDBM50642446(CHEMBL5569615)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642449BDBM50642449(CHEMBL5569327)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642447BDBM50642447(CHEMBL5565442)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642452BDBM50642452(CHEMBL5574847)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642450BDBM50642450(CHEMBL5575305)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured for 1 hr in presence of NADPH by absorbance based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed