Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50020054
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 230nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625845(CHEMBL5427814)
Affinity DataIC50: 350nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625842(CHEMBL5419490)
Affinity DataIC50: 370nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 470nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625842(CHEMBL5419490)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625845(CHEMBL5427814)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 5.38E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625845(CHEMBL5427814)
Affinity DataIC50: 6.67E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625842(CHEMBL5419490)
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 7.81E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625841(CHEMBL5401248)
Affinity DataIC50: 3.84E+5nMAssay Description:Inhibition of human carbonic anhydrase II esterase activity using p-nitrophenol acetate as substrate and measured for 3 mins by UV/visible spectropho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625840(CHEMBL5423078)
Affinity DataIC50: 4.22E+5nMAssay Description:Inhibition of human carbonic anhydrase II esterase activity using p-nitrophenol acetate as substrate and measured for 3 mins by UV/visible spectropho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed