Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50021241
LigandPNGBDBM50638607(CHEMBL5563355)
Affinity DataKd:  4.60nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 70 mins by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638607(CHEMBL5563355)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 70 mins by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 70 mins by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataKd:  9.10nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50017293(CHEMBL3287735 | US10647700, Compound GSK126)
Affinity DataIC50: 10nMAssay Description:Inhibition of EZH2 (unknown origin) in PRC2 complex preincubated for 30 mins followed by H3K27me peptide and SAM addition incubated for 3 hrs by hist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638606(CHEMBL5555822)
Affinity DataIC50: 15nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 70 mins by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638606(CHEMBL5555822)
Affinity DataKd:  15nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 17nMAssay Description:Inhibition of EZH2 (unknown origin) in PRC2 complex preincubated for 30 mins followed by H3K27me peptide and SAM addition incubated for 3 hrs by hist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638607(CHEMBL5563355)
Affinity DataIC50: 27nMAssay Description:Inhibition of EZH2 (unknown origin) in PRC2 complex preincubated for 30 mins followed by H3K27me peptide and SAM addition incubated for 3 hrs by hist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638614(CHEMBL5559862)
Affinity DataKd:  28nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638615(CHEMBL5564476)
Affinity DataKd:  37nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50017293(CHEMBL3287735 | US10647700, Compound GSK126)
Affinity DataKd:  61nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638616(CHEMBL5559875)
Affinity DataKd:  65nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638611(CHEMBL5564620)
Affinity DataKd:  112nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638609(CHEMBL5559941)
Affinity DataKd:  116nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638613(CHEMBL5542111)
Affinity DataKd:  125nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638617(CHEMBL5566328)
Affinity DataKd:  213nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638612(CHEMBL5567883)
Affinity DataKd:  287nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638608(CHEMBL5556932)
Affinity DataKd:  794nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50638610(CHEMBL5561718)
Affinity DataKd:  1.99E+3nMAssay Description:Binding affinity to EZH2 (unknown origin) in PRC2 complex assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed